Mission

To develop precision medicines that target hypoxic (low oxygen) areas in tumours that conventional chemotherapy, immunotherapy and radiotherapy do not treat. Hypoxia is recognized as a key resistance factor affecting all cancer treatments

OncoTherics Technology
unidirectional Hypoxia Activated Prodrugs (uHAPs)

HYPOXIC CANCER CELLS
THE PROBLEM
HYPOXIC CANCER CELLS
CONVENTIONAL THERAPIES
DO NOT TREAT HYPOXIC CANCER CELLS
uHAPs REACH
HYPOXIC CANCER CELLS
uHAPs KILL
HYPOXIC CANCER CELLS

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Team
About us
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science
Science
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Pipeline

uHAPs: a tumour agnostic therapy

  • 2 lead assets, at different phases of development
  • uHAP 1: extensive Phase I experience, excellent safety profile
  • uHAP 2: second generation molecule - broad applications in many tumours

The uHAP Competitive Advantage

Non-Cytotoxic Prodrugs

minimal effects compared to conventional cytotoxics

Excellent Penetration

across all tissues, including the blood brain barrier

Irreversible Metabolism

to effective and persistent TOPO 2 Inhibitors at target hypoxic sites

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Contact

OncoTherics Poland Sp. z o.o.
ul. prof. Michała Bobrzyńskiego 14
30-348 Kraków
Poland

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